12. 12. EUBN Q4 2023 Aug23327 TNC Bio is a biotechnology research company working to provide the international cell culture community with defined and animal-free solutions. The company’s flagship product, XerumFree™, is the world’s first universal, fully defined, and animal-free Foetal Bovine Serum (FBS) replacement for primary cells and cell lines. For its excellent standard of client service and its highly effective product, TNC Bio was recently named Best Animal-Free FBS Alternative Producer, Netherlands, in the Benelux Enterprise Awards 2023. Derived from the blood of a cow foetus, Foetal Bovine Serum (FBS) is commonly used as a growth supplement in cell culture applications because of its high content of embryonic growth-promoting factors. In recent decades, there has been a significant increase in regulatory pressure to move away from the use of FBS in the field of cell culture. This is due to the risk of contaminations with viruses and prions, as well as the need for traceability records. For this reason, there is a demand for an FBS replacement that is chemically defined and completely free of animal components. To fulfil this need, TNC Bio presents XerumFree™, an efficient and fully defined cell culture supplement. Designed for use in research and development as well as manufacturing applications, it is guaranteed to be free from any product derived from animal or human material and has an ultra-low protein content. The proteins present in XerumFree™ are produced by a recombinant bacterial process in animal component-free (ACF) media. TNC Bio understands that its clients cannot afford to encounter unexpected challenges that cause gaps in their vaccine production processes, for example in terms of quality, cost, or supply. The company helps them avoid these difficult situations in a number of ways. Firstly, TNC Bio guarantees the quality of every batch of XerumFree™ by ensuring that it is fully defined. Many other FBS alternatives contain hydrolysates, plant extracts, or animal/human proteins, which can negatively affect consistency from batch to batch and reduce control over the culture environment. Unlike its competitors, TNC Bio’s product consists only of compounds that are highly purified chemicals derived from either synthetic or recombinant origin. This guarantees an extremely high level of consistency from batch to batch as well as a full traceability record. Secondly, to help clients avoid issues related to supply, TNC Bio is able to ensure that their production facilities are provided with a consistent supply of XerumFree™. It can do this thanks to its own robust manufacturing facilities, which are equipped for high levels of volume production and can be flexibly scaled up when needed. As well as this, the raw materials used to make XerumFree™ are not sensitive to issues related to volatility, fluctuations, and availability. This means that clients can benefit from a reduced risk of supply chain breakdown. XerumFree™ is generally packaged for use in research and development in 100ml or 500ml Nalgene PETG bottles. For production purposes where volume is higher, TNC Bio can deliver packaging of all shapes and sizes to suit clients’ requirements. Whether it’s bags or vessels, the company will aim to source and deliver the packaging they need. As a result of its commitment to its clients as well as its innovative product, which serves as an effective alternative to the use of FBS in cell culture applications, TNC Bio has been named Best Animal-Free FBS Alternative Producer, Netherlands, in the Benelux Enterprise Awards 2023. We congratulate the company on its success in this prestigious awards programme and wish its team the best of luck in the years to come. Contact Details Contact: Maarten van Tiel Company: TNC Bio BV Web Address: tncbio.com Best Animal-Free FBS Alternative Producer 2023 - Netherlands
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